Really customisable layouts

Hello,

Can you tell me if I am able to create a layout like this at www.designwebs.co.uk/taylormade with themeframe?

I want a slideshow to be the large image on top right of the home page and go right to the top of the page, so there will be no main header along the top, and the header to be a small box on the top left above the vertical navigation.

I have purchased headway, but am struggling to get on with it as there is so much coding required just to get it to look like the site mentioned above.

Thank you.